Bromotrimethylsilane

98%

  • Product Code: 88321
  Alias:    Trimethylbromosilane
  CAS:    2857-97-8
Molecular Weight: 153.09 g./mol Molecular Formula: C₃H₉BrSi
EC Number: 220-672-0 MDL Number: MFCD00000048
Melting Point: -43 °C Boiling Point: 79 °C(lit.)
Density: 1.16 g/mL at 25 °C(lit.) Storage Condition: 2~8°C
Product Description: Bromotrimethylsilane is widely used in organic synthesis as a reagent for introducing the trimethylsilyl group into molecules. It is particularly effective in protecting alcohols and phenols by converting them into their corresponding trimethylsilyl ethers, which are stable under various reaction conditions. This protection allows for selective reactions to be carried out on other functional groups within the molecule. Additionally, it is employed in the cleavage of ethers, especially methyl ethers, facilitating the deprotection of hydroxyl groups. In peptide synthesis, it serves as a deprotecting agent for tert-butyl esters and ethers, enabling the formation of complex peptide structures. Its role in the synthesis of silicon-containing compounds is also notable, contributing to the development of materials with unique properties.
Product Specification:
Test Specification
PurityGC 98-100
REFRACTIVE INDEX N20D 1.42-1.425
SPECIFIC GRAVITY 2020C 1.17-1.2
APPEARANCE Colorless to light yellow liquid
INFRARED SPECTRUM Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
25.000 10-20 days $27.71
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100.000 10-20 days $70.92
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500.000 10-20 days $241.86
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2500.000 10-20 days $1,032.74
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Bromotrimethylsilane
Bromotrimethylsilane is widely used in organic synthesis as a reagent for introducing the trimethylsilyl group into molecules. It is particularly effective in protecting alcohols and phenols by converting them into their corresponding trimethylsilyl ethers, which are stable under various reaction conditions. This protection allows for selective reactions to be carried out on other functional groups within the molecule. Additionally, it is employed in the cleavage of ethers, especially methyl ethers, facilitating the deprotection of hydroxyl groups. In peptide synthesis, it serves as a deprotecting agent for tert-butyl esters and ethers, enabling the formation of complex peptide structures. Its role in the synthesis of silicon-containing compounds is also notable, contributing to the development of materials with unique properties.
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