(Trimethylsilyl)methylmagnesium chloride

1.0 M solution in THF,Mkseal

  • Product Code: 88859
  CAS:    13170-43-9
Molecular Weight: 146.97 g./mol Molecular Formula: C₄H₁₁ClMgSi
EC Number: MDL Number: MFCD00009916
Melting Point: Boiling Point:
Density: 1.04 Storage Condition: 2~8 ℃
Product Description: This chemical is primarily used in organic synthesis as a versatile reagent for introducing the (trimethylsilyl)methyl group into various organic compounds. It is particularly valuable in the preparation of silicon-containing molecules, which are often intermediates in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. In medicinal chemistry, it is employed to create silicon-substituted analogs of biologically active compounds, enhancing their stability or altering their pharmacokinetic properties. Additionally, it is used in the development of organosilicon polymers and resins, which find applications in coatings, adhesives, and electronic materials due to their thermal stability and mechanical properties. The reagent is also utilized in the synthesis of complex natural products and fine chemicals, where its ability to form carbon-silicon bonds is leveraged to construct intricate molecular architectures. Its reactivity with carbonyl compounds, such as aldehydes and ketones, makes it a useful tool for creating alcohols and other functionalized intermediates. Overall, it plays a critical role in advancing research and industrial processes in chemistry and materials science.
Product Specification:
Test Specification
CONCENTRATION 0.95-1.1
APPEARANCE COLORLESS TO ORANGE TO BROWN TO BROWN-BLACK LIQUID
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
100.000 10-20 days ฿2,860.00
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(Trimethylsilyl)methylmagnesium chloride
This chemical is primarily used in organic synthesis as a versatile reagent for introducing the (trimethylsilyl)methyl group into various organic compounds. It is particularly valuable in the preparation of silicon-containing molecules, which are often intermediates in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. In medicinal chemistry, it is employed to create silicon-substituted analogs of biologically active compounds, enhancing their stability or altering their pharmacokinetic properties. Additionally, it is used in the development of organosilicon polymers and resins, which find applications in coatings, adhesives, and electronic materials due to their thermal stability and mechanical properties. The reagent is also utilized in the synthesis of complex natural products and fine chemicals, where its ability to form carbon-silicon bonds is leveraged to construct intricate molecular architectures. Its reactivity with carbonyl compounds, such as aldehydes and ketones, makes it a useful tool for creating alcohols and other functionalized intermediates. Overall, it plays a critical role in advancing research and industrial processes in chemistry and materials science.
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