4-Fluoro-2-(trifluoromethyl)benzeneboronic acid

98%

  • Product Code: 90591
  Alias:    4-Fluoro-2-trifluoromethylphenylboronic acid
  CAS:    182344-16-7
Molecular Weight: 207.92 g./mol Molecular Formula: C₇H₅BF₄O₂
EC Number: MDL Number: MFCD08062379
Melting Point: 183-186°C Boiling Point:
Density: Storage Condition: room temperature
Product Description: This chemical is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate for the construction of complex aromatic compounds, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl structures that are often found in active pharmaceutical ingredients (APIs). Additionally, it is employed in the preparation of fluorinated organic compounds, which are valuable in medicinal chemistry due to their enhanced metabolic stability and bioavailability. The compound’s trifluoromethyl group further contributes to its utility in creating molecules with unique electronic and steric properties, making it a versatile tool in drug discovery and material science.
Product Specification:
Test Specification
Melting point 183 186?
PURITYHPLC 98 100%
APPEARANCE White to off-white powder or solid or chunks
INFRARED SPECTROMETRY Conforms to Structure
PROTON NMR SPECTRUM Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.250 10-20 days ฿330.00
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1.000 10-20 days ฿410.00
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5.000 10-20 days ฿1,300.00
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25.000 10-20 days ฿5,330.00
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4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
This chemical is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate for the construction of complex aromatic compounds, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl structures that are often found in active pharmaceutical ingredients (APIs). Additionally, it is employed in the preparation of fluorinated organic compounds, which are valuable in medicinal chemistry due to their enhanced metabolic stability and bioavailability. The compound’s trifluoromethyl group further contributes to its utility in creating molecules with unique electronic and steric properties, making it a versatile tool in drug discovery and material science.
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