DBCO-CONH-S-S-NHS ester
95%
- Product Code: 95981
CAS:
1435934-53-4
| Molecular Weight: | 565.66 g./mol | Molecular Formula: | C₂₈H₂₇N₃O₆S₂ |
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| Density: | Storage Condition: | -20°C |
Product Description:
This compound is widely used in bioorthogonal chemistry for labeling and conjugating biomolecules. Its DBCO group enables rapid and selective reactions with azides through strain-promoted alkyne-azide cycloaddition (SPAAC), making it ideal for live-cell imaging and protein modification without interfering with biological processes. The NHS ester group allows for efficient coupling with primary amines, facilitating the attachment to proteins, peptides, or other amine-containing molecules. The disulfide bond (S-S) provides a cleavable linkage, enabling controlled release of conjugated molecules under reducing conditions, which is particularly useful in drug delivery systems and targeted therapies. Its applications span across bioconjugation, antibody-drug conjugates, and the development of diagnostic tools.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | €1,466.18 |
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DBCO-CONH-S-S-NHS ester
This compound is widely used in bioorthogonal chemistry for labeling and conjugating biomolecules. Its DBCO group enables rapid and selective reactions with azides through strain-promoted alkyne-azide cycloaddition (SPAAC), making it ideal for live-cell imaging and protein modification without interfering with biological processes. The NHS ester group allows for efficient coupling with primary amines, facilitating the attachment to proteins, peptides, or other amine-containing molecules. The disulfide bond (S-S) provides a cleavable linkage, enabling controlled release of conjugated molecules under reducing conditions, which is particularly useful in drug delivery systems and targeted therapies. Its applications span across bioconjugation, antibody-drug conjugates, and the development of diagnostic tools.
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