Digitonin
50%, water soluble
- Product Code: 96048
Alias:
digitonin, digitonin
CAS:
11024-24-1
| Molecular Weight: | 1229.31 g./mol | Molecular Formula: | C₅₆H₉₂O₂₉ |
|---|---|---|---|
| EC Number: | 234-255-6 | MDL Number: | MFCD00077729 |
| Melting Point: | 230-240 °C (dec.)(lit.) | Boiling Point: | |
| Density: | Storage Condition: | room temperature |
Product Description:
Digitonin is widely used in biochemical research for its ability to solubilize membrane proteins. It selectively binds to cholesterol in cell membranes, making it a valuable tool for extracting membrane-bound proteins without denaturing them. This property is particularly useful in studies involving membrane receptor isolation and purification. Additionally, digitonin is employed in permeabilizing cell membranes, allowing researchers to access intracellular components for experiments such as immunostaining or enzyme activity assays. Its application extends to the study of mitochondrial function, where it is used to selectively permeabilize the outer mitochondrial membrane while leaving the inner membrane intact.
Product Specification:
| Test | Specification |
|---|---|
| Purity | 50 |
| ACETIC ACID | -50--47 |
| WATER BY KARL FISCHER | 0-6 |
| APPEARANCE | WHITE TO YELLOWISH POWDER |
| INFRARED SPECTRUM | Conforms to Structure |
| SENSITIVENESS TEST | PASS |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $225.51 |
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| 0.500 | 10-20 days | $853.34 |
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| 1.000 | 10-20 days | $1,525.36 |
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Digitonin
Digitonin is widely used in biochemical research for its ability to solubilize membrane proteins. It selectively binds to cholesterol in cell membranes, making it a valuable tool for extracting membrane-bound proteins without denaturing them. This property is particularly useful in studies involving membrane receptor isolation and purification. Additionally, digitonin is employed in permeabilizing cell membranes, allowing researchers to access intracellular components for experiments such as immunostaining or enzyme activity assays. Its application extends to the study of mitochondrial function, where it is used to selectively permeabilize the outer mitochondrial membrane while leaving the inner membrane intact.
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