Guanidine hydrochloride

AR,99.0%

  • Product Code: 96071
  Alias:    Guanidine hydrochloride; urea hydrochloride, guanidine hydrochloride, carbamidine hydrochloride, guanidine monohydrochloride
  CAS:    50-01-1
Molecular Weight: 95.53 g./mol Molecular Formula: CH₅N₃HCl
EC Number: 200-002-3 MDL Number: MFCD00013026
Melting Point: 180-185 °C(lit.) Boiling Point:
Density: 1.345 g/cm3 at 20 °C(lit.) Storage Condition: room temperature
Product Description: Guanidine hydrochloride is widely used in molecular biology for protein denaturation. It helps in unfolding proteins by disrupting hydrogen bonds and hydrophobic interactions, making it valuable in studying protein structure and function. It is also employed in RNA extraction processes, where it aids in breaking down cell membranes and inactivating nucleases, ensuring the integrity of RNA samples. Additionally, it serves as a chaotropic agent in affinity chromatography, facilitating the purification of proteins and nucleic acids. In biochemistry, it is utilized to solubilize inclusion bodies, enabling the refolding of recombinant proteins. Its role in these applications highlights its importance in research and biotechnological processes.
Product Specification:
Test Specification
ASSAY 98.5 101.5%
WATER BY KARL FISCHER 0 0.5%
APPEARANCE White crystalline powder
Solubility Color Colorless to light yellow
Solubility Turbidity 6M in H2O (286 g to 500 ml),Clear
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
100.000 10-20 days €9.76
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500.000 10-20 days €29.02
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5000.000 10-20 days €244.82
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Guanidine hydrochloride
Guanidine hydrochloride is widely used in molecular biology for protein denaturation. It helps in unfolding proteins by disrupting hydrogen bonds and hydrophobic interactions, making it valuable in studying protein structure and function. It is also employed in RNA extraction processes, where it aids in breaking down cell membranes and inactivating nucleases, ensuring the integrity of RNA samples. Additionally, it serves as a chaotropic agent in affinity chromatography, facilitating the purification of proteins and nucleic acids. In biochemistry, it is utilized to solubilize inclusion bodies, enabling the refolding of recombinant proteins. Its role in these applications highlights its importance in research and biotechnological processes.
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