1-Hydroxy-7-azabenzotriazole
~0.6 M in DMF
- Product Code: 96154
Alias:
1-Hydroxy-7-azobenzotriazole (HOAt); N-Hydroxy-7-azobenzotriazole
CAS:
39968-33-7
| Molecular Weight: | 136.11 g./mol | Molecular Formula: | C₅H₄N₄O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00210053 | |
| Melting Point: | 213-216°C | Boiling Point: | |
| Density: | 0.973 g/mL at 20 °C | Storage Condition: | room temperature |
Product Description:
1-Hydroxy-7-azabenzotriazole is widely used in peptide synthesis as an activating agent. It enhances the coupling efficiency of amino acids, particularly in solid-phase peptide synthesis. This compound helps reduce racemization, ensuring higher purity and yield of the desired peptide products. It is also employed in organic synthesis to facilitate the formation of amide bonds, making it valuable in the production of pharmaceuticals and bioactive compounds. Additionally, it acts as a stabilizer in certain chemical reactions, preventing unwanted side reactions and improving overall reaction outcomes. Its role in improving selectivity and efficiency makes it a crucial reagent in synthetic chemistry.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Very Light Yellow to Dark Yellow and Very Light Green-Yellow to Dark Green- Yellow Liquid |
| CONCENTRATION MOLL | 0.50-0.70 |
| WATER | 0 % 1.0 % |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | ฿14,120.00 |
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| 100.000 | 10-20 days | ฿36,780.00 |
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1-Hydroxy-7-azabenzotriazole
1-Hydroxy-7-azabenzotriazole is widely used in peptide synthesis as an activating agent. It enhances the coupling efficiency of amino acids, particularly in solid-phase peptide synthesis. This compound helps reduce racemization, ensuring higher purity and yield of the desired peptide products. It is also employed in organic synthesis to facilitate the formation of amide bonds, making it valuable in the production of pharmaceuticals and bioactive compounds. Additionally, it acts as a stabilizer in certain chemical reactions, preventing unwanted side reactions and improving overall reaction outcomes. Its role in improving selectivity and efficiency makes it a crucial reagent in synthetic chemistry.
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