3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
97%
- Product Code: 97170
CAS:
81246-81-3
| Molecular Weight: | 660.83 g./mol | Molecular Formula: | C₃₆H₄₄N₂O₈Si |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
This chemical is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a protected nucleoside, where the tert-butyldimethylsilyl (TBDMS) group shields the 3'-hydroxyl position and the dimethoxytrityl (DMT) group protects the 5'-hydroxyl position. These protective groups are crucial during the stepwise assembly of DNA or RNA strands, ensuring that reactions occur selectively at the desired sites. The compound is especially valuable in solid-phase oligonucleotide synthesis, where it allows for the precise construction of sequences used in applications such as PCR, gene editing, and antisense therapy. Its stability and ease of deprotection make it a reliable building block in the production of custom nucleic acids for research and therapeutic purposes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿3,186.00 |
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| 1.000 | 10-20 days | ฿8,271.00 |
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3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
This chemical is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a protected nucleoside, where the tert-butyldimethylsilyl (TBDMS) group shields the 3'-hydroxyl position and the dimethoxytrityl (DMT) group protects the 5'-hydroxyl position. These protective groups are crucial during the stepwise assembly of DNA or RNA strands, ensuring that reactions occur selectively at the desired sites. The compound is especially valuable in solid-phase oligonucleotide synthesis, where it allows for the precise construction of sequences used in applications such as PCR, gene editing, and antisense therapy. Its stability and ease of deprotection make it a reliable building block in the production of custom nucleic acids for research and therapeutic purposes.
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