4-N-Benzoyl-5'-O-(tert-butyldimethylsilyl)-5-[3-(2,2,2-trifluoroacetamido)-prop-1-ynyl]-2'-deoxycytidine

95%

  • Product Code: 97191
  CAS:    666847-67-2
Molecular Weight: 594.7 g./mol Molecular Formula: C₂₇H₃₃F₃N₄O₆Si
EC Number: MDL Number:
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Density: Storage Condition: 2-8°C, dry, airtight
Product Description: This compound is primarily utilized in the field of nucleotide chemistry and medicinal research, particularly in the synthesis of modified nucleosides. Its structure, featuring a trifluoroacetamido group and a tert-butyldimethylsilyl (TBDMS) protecting group, makes it a valuable intermediate in the development of oligonucleotides for therapeutic applications. The trifluoroacetamido moiety enhances stability and reactivity, allowing for precise modifications in nucleic acid sequences. Additionally, the TBDMS group protects the hydroxyl functionality during synthetic processes, ensuring selective reactions. This compound is often employed in the preparation of antisense oligonucleotides, which are used in gene silencing and targeted therapy for genetic disorders and viral infections. Its unique properties also make it suitable for research in drug delivery systems, where modified nucleosides are designed to improve bioavailability and therapeutic efficacy.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days ฿41,184.00
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4-N-Benzoyl-5'-O-(tert-butyldimethylsilyl)-5-[3-(2,2,2-trifluoroacetamido)-prop-1-ynyl]-2'-deoxycytidine
This compound is primarily utilized in the field of nucleotide chemistry and medicinal research, particularly in the synthesis of modified nucleosides. Its structure, featuring a trifluoroacetamido group and a tert-butyldimethylsilyl (TBDMS) protecting group, makes it a valuable intermediate in the development of oligonucleotides for therapeutic applications. The trifluoroacetamido moiety enhances stability and reactivity, allowing for precise modifications in nucleic acid sequences. Additionally, the TBDMS group protects the hydroxyl functionality during synthetic processes, ensuring selective reactions. This compound is often employed in the preparation of antisense oligonucleotides, which are used in gene silencing and targeted therapy for genetic disorders and viral infections. Its unique properties also make it suitable for research in drug delivery systems, where modified nucleosides are designed to improve bioavailability and therapeutic efficacy.
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