N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
97%
- Product Code: 97279
CAS:
123956-65-0
| Molecular Weight: | 701.88 g./mol | Molecular Formula: | C₃₈H₄₇N₃O₈Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22124263 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.19±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C |
Product Description:
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of nucleic acid chemistry. It serves as a protected nucleoside intermediate, ensuring selective reactivity during the construction of DNA or RNA sequences. The tert-butyldimethylsilyl (TBDMS) group protects the 3'-hydroxyl, while the dimethoxytrityl (DMT) group safeguards the 5'-hydroxyl, allowing for controlled stepwise assembly in solid-phase synthesis. The acetyl group on the N4 position of cytidine prevents unwanted side reactions during the process. This compound is essential in producing high-purity oligonucleotides for applications such as gene synthesis, PCR primers, and antisense therapeutics. Its use is critical in research and development of genetic engineering, molecular diagnostics, and therapeutic oligonucleotides.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | $262.18 |
+
-
|
| 1.000 | 10-20 days | $750.38 |
+
-
|
N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of nucleic acid chemistry. It serves as a protected nucleoside intermediate, ensuring selective reactivity during the construction of DNA or RNA sequences. The tert-butyldimethylsilyl (TBDMS) group protects the 3'-hydroxyl, while the dimethoxytrityl (DMT) group safeguards the 5'-hydroxyl, allowing for controlled stepwise assembly in solid-phase synthesis. The acetyl group on the N4 position of cytidine prevents unwanted side reactions during the process. This compound is essential in producing high-purity oligonucleotides for applications such as gene synthesis, PCR primers, and antisense therapeutics. Its use is critical in research and development of genetic engineering, molecular diagnostics, and therapeutic oligonucleotides.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
$0.00
$0.00
Total :