N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
98%
- Product Code: 97300
CAS:
199593-09-4
| Molecular Weight: | 801.86 g./mol | Molecular Formula: | C₄₂H₅₂N₅O₉P |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD12912403 | |
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| Density: | Storage Condition: | 2-8℃, dry |
Product Description:
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of nucleic acid research and therapeutic development. It serves as a key building block in the solid-phase synthesis of modified RNA sequences, enabling the incorporation of 2'-O-methylcytidine into oligonucleotide chains. This modification enhances the stability and nuclease resistance of RNA molecules, making it valuable for applications in antisense technology, siRNA (small interfering RNA) therapeutics, and RNA-based drug development. Its protective groups, such as DMT (dimethoxytrityl) and CE (cyanoethyl), ensure controlled and efficient coupling during synthesis, while the phosphoramidite moiety facilitates the stepwise assembly of the oligonucleotide chain. This compound is essential for producing RNA analogs with improved pharmacokinetic properties for use in gene silencing, diagnostics, and targeted therapies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | $1,974.21 |
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N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of nucleic acid research and therapeutic development. It serves as a key building block in the solid-phase synthesis of modified RNA sequences, enabling the incorporation of 2'-O-methylcytidine into oligonucleotide chains. This modification enhances the stability and nuclease resistance of RNA molecules, making it valuable for applications in antisense technology, siRNA (small interfering RNA) therapeutics, and RNA-based drug development. Its protective groups, such as DMT (dimethoxytrityl) and CE (cyanoethyl), ensure controlled and efficient coupling during synthesis, while the phosphoramidite moiety facilitates the stepwise assembly of the oligonucleotide chain. This compound is essential for producing RNA analogs with improved pharmacokinetic properties for use in gene silencing, diagnostics, and targeted therapies.
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