Pyruvate Dehydrogenase, from porcine heart
buffered aqueous glycerol solution, 0.1-1.0 units/mg protein (Lowry)
- Product Code: 98861
CAS:
9014-20-4
| Molecular Weight: | Molecular Formula: | ||
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00132145 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | −20°C |
Product Description:
Pyruvate dehydrogenase from porcine heart is widely used in biochemical research to study cellular metabolism, particularly the conversion of pyruvate to acetyl-CoA, a critical step in the tricarboxylic acid (TCA) cycle. It serves as a key enzyme in understanding energy production pathways and metabolic regulation in mitochondria. Researchers utilize this enzyme to investigate enzyme kinetics, substrate specificity, and the effects of inhibitors or activators on its function. It is also employed in diagnostic assays to measure pyruvate dehydrogenase activity in clinical studies related to metabolic disorders, such as pyruvate dehydrogenase deficiency. Additionally, it aids in the development of therapeutic strategies targeting metabolic diseases and cancer, where altered mitochondrial function plays a significant role.
Product Specification:
| Test | Specification |
|---|---|
| mg proteinml Lowry | 5.0 |
| unitsmg proteinpH 7.4 30 | 0.1 - 1.0 |
| Impurity by Enzymatic | 15 % |
| Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 5.000 | 10-20 days | ฿31,200.00 |
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| 10.000 | 10-20 days | ฿59,600.00 |
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Pyruvate Dehydrogenase, from porcine heart
Pyruvate dehydrogenase from porcine heart is widely used in biochemical research to study cellular metabolism, particularly the conversion of pyruvate to acetyl-CoA, a critical step in the tricarboxylic acid (TCA) cycle. It serves as a key enzyme in understanding energy production pathways and metabolic regulation in mitochondria. Researchers utilize this enzyme to investigate enzyme kinetics, substrate specificity, and the effects of inhibitors or activators on its function. It is also employed in diagnostic assays to measure pyruvate dehydrogenase activity in clinical studies related to metabolic disorders, such as pyruvate dehydrogenase deficiency. Additionally, it aids in the development of therapeutic strategies targeting metabolic diseases and cancer, where altered mitochondrial function plays a significant role.
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