(S,R,S)-AHPC-PEG1-N3
≥98%
- Product Code: 99242
CAS:
2101200-09-1
| Molecular Weight: | 557.67 g./mol | Molecular Formula: | C₂₆H₃₅N₇O₅S |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
Used primarily in the field of targeted protein degradation, this compound plays a crucial role in the development of PROTACs (Proteolysis Targeting Chimaeras). It facilitates the selective degradation of specific proteins by linking an E3 ubiquitin ligase to a target protein, thereby marking it for destruction by the proteasome. This mechanism is particularly valuable in cancer research, where it helps in the elimination of oncogenic proteins that are otherwise difficult to target with traditional inhibitors. Additionally, its PEG linker enhances solubility and bioavailability, making it more effective in cellular environments. The azide group allows for further functionalization through click chemistry, enabling the attachment of various targeting ligands or probes for diagnostic purposes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿35,000.00 |
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| 0.500 | 10-20 days | ฿150,000.00 |
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(S,R,S)-AHPC-PEG1-N3
Used primarily in the field of targeted protein degradation, this compound plays a crucial role in the development of PROTACs (Proteolysis Targeting Chimaeras). It facilitates the selective degradation of specific proteins by linking an E3 ubiquitin ligase to a target protein, thereby marking it for destruction by the proteasome. This mechanism is particularly valuable in cancer research, where it helps in the elimination of oncogenic proteins that are otherwise difficult to target with traditional inhibitors. Additionally, its PEG linker enhances solubility and bioavailability, making it more effective in cellular environments. The azide group allows for further functionalization through click chemistry, enabling the attachment of various targeting ligands or probes for diagnostic purposes.
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