U-0521
≥98%
- Product Code: 99256
CAS:
5466-89-7
| Molecular Weight: | 180.2 g./mol | Molecular Formula: | C₁₀H₁₂O₃ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
U-0521 is primarily utilized in research settings as a selective inhibitor of the enzyme 15-hydroxyprostaglandin dehydrogenase (15-PGDH). This enzyme plays a crucial role in the metabolism of prostaglandins, which are involved in various physiological processes such as inflammation, pain, and fever. By inhibiting 15-PGDH, U-0521 helps to increase the levels of prostaglandins in tissues, making it a valuable tool for studying the biological effects and therapeutic potential of these lipid compounds.
In experimental models, U-0521 has been used to investigate the role of prostaglandins in tissue repair and regeneration. For instance, studies have shown that elevating prostaglandin levels through 15-PGDH inhibition can enhance wound healing and promote tissue regeneration in various organs. This has led to interest in its potential applications in regenerative medicine, particularly for conditions where tissue repair is impaired.
Additionally, U-0521 has been employed in pharmacological research to explore its effects on inflammatory diseases. By modulating prostaglandin levels, researchers aim to better understand the underlying mechanisms of inflammation and develop targeted therapies for conditions such as arthritis, inflammatory bowel disease, and other chronic inflammatory disorders.
Overall, U-0521 serves as a critical research tool for elucidating the functions of prostaglandins and their regulatory pathways, with potential implications for developing novel treatments for a range of medical conditions.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿16,200.00 |
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| 0.010 | 10-20 days | ฿26,100.00 |
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U-0521
U-0521 is primarily utilized in research settings as a selective inhibitor of the enzyme 15-hydroxyprostaglandin dehydrogenase (15-PGDH). This enzyme plays a crucial role in the metabolism of prostaglandins, which are involved in various physiological processes such as inflammation, pain, and fever. By inhibiting 15-PGDH, U-0521 helps to increase the levels of prostaglandins in tissues, making it a valuable tool for studying the biological effects and therapeutic potential of these lipid compounds.
In experimental models, U-0521 has been used to investigate the role of prostaglandins in tissue repair and regeneration. For instance, studies have shown that elevating prostaglandin levels through 15-PGDH inhibition can enhance wound healing and promote tissue regeneration in various organs. This has led to interest in its potential applications in regenerative medicine, particularly for conditions where tissue repair is impaired.
Additionally, U-0521 has been employed in pharmacological research to explore its effects on inflammatory diseases. By modulating prostaglandin levels, researchers aim to better understand the underlying mechanisms of inflammation and develop targeted therapies for conditions such as arthritis, inflammatory bowel disease, and other chronic inflammatory disorders.
Overall, U-0521 serves as a critical research tool for elucidating the functions of prostaglandins and their regulatory pathways, with potential implications for developing novel treatments for a range of medical conditions.
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