A-966492
99%
- Product Code: 99335
CAS:
934162-61-5
| Molecular Weight: | 324.35 g./mol | Molecular Formula: | C₁₈H₁₇FN₄O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD17215207 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
A-966492 is primarily utilized in research settings as a potent and selective inhibitor of PARP-1 and PARP-2 enzymes. Its application is significant in studying the role of PARP enzymes in DNA repair mechanisms, particularly in the context of cancer research. By inhibiting PARP activity, it helps researchers understand how cancer cells respond to DNA damage and explore potential therapeutic strategies. Additionally, it is used in preclinical studies to evaluate the efficacy of PARP inhibitors in enhancing the effects of chemotherapy or radiation therapy, particularly in cancers with defective DNA repair pathways, such as BRCA-mutated cancers.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to off white powder |
| PURITY | 99-100 |
| SOLUBILITY | 64 mg/mL(DMSO) |
| Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | $319.36 |
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A-966492
A-966492 is primarily utilized in research settings as a potent and selective inhibitor of PARP-1 and PARP-2 enzymes. Its application is significant in studying the role of PARP enzymes in DNA repair mechanisms, particularly in the context of cancer research. By inhibiting PARP activity, it helps researchers understand how cancer cells respond to DNA damage and explore potential therapeutic strategies. Additionally, it is used in preclinical studies to evaluate the efficacy of PARP inhibitors in enhancing the effects of chemotherapy or radiation therapy, particularly in cancers with defective DNA repair pathways, such as BRCA-mutated cancers.
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