ABBV-744
99%
- Product Code: 99348
CAS:
2138861-99-9
| Molecular Weight: | 491.55 g./mol | Molecular Formula: | C₂₈H₃₀FN₃O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
ABBV-744 is primarily utilized in the field of oncology, specifically targeting cancers that are driven by the overexpression of BET proteins. It functions as a selective inhibitor of the BD2 domain within BET proteins, which plays a crucial role in regulating gene expression related to cancer cell growth and survival. This selectivity allows ABBV-744 to potentially reduce off-target effects compared to pan-BET inhibitors, making it a promising candidate for treating hematologic malignancies such as acute myeloid leukemia (AML) and multiple myeloma. Its application is currently under investigation in clinical trials to assess its efficacy and safety in patients with these types of cancers.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | powder |
| PURITY | 98.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿6,800.00 |
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| 0.005 | 10-20 days | ฿16,200.00 |
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| 0.010 | 10-20 days | ฿24,710.00 |
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ABBV-744
ABBV-744 is primarily utilized in the field of oncology, specifically targeting cancers that are driven by the overexpression of BET proteins. It functions as a selective inhibitor of the BD2 domain within BET proteins, which plays a crucial role in regulating gene expression related to cancer cell growth and survival. This selectivity allows ABBV-744 to potentially reduce off-target effects compared to pan-BET inhibitors, making it a promising candidate for treating hematologic malignancies such as acute myeloid leukemia (AML) and multiple myeloma. Its application is currently under investigation in clinical trials to assess its efficacy and safety in patients with these types of cancers.
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| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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