AG-1478
>98%
- Product Code: 99438
CAS:
153436-53-4
| Molecular Weight: | 315.75 g./mol | Molecular Formula: | C₁₆H₁₄ClN₃O₂ |
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| Density: | Storage Condition: | -20℃ |
Product Description:
AG-1478 is widely used in research settings as a selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It is particularly valuable in studying the role of EGFR in cellular processes such as proliferation, differentiation, and survival. Researchers utilize AG-1478 to investigate its effects on cancer cell lines, as EGFR signaling is often dysregulated in various types of cancers. By inhibiting EGFR, AG-1478 helps in understanding the mechanisms of tumor growth and in evaluating potential therapeutic strategies. Additionally, it is employed in studies related to wound healing and tissue regeneration, where EGFR signaling plays a critical role. Its application extends to neuroscience research, where it is used to explore EGFR's involvement in neuronal development and function. Overall, AG-1478 serves as a crucial tool in biomedical research for dissecting EGFR-related pathways and their implications in health and disease.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Faint Yellow to Yellow Powder or crystals |
| PURITY | 98-100 |
| NMR | Consistent with structure |
| Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | Ft61,843.38 |
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| 0.050 | 10-20 days | Ft278,726.17 |
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AG-1478
AG-1478 is widely used in research settings as a selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It is particularly valuable in studying the role of EGFR in cellular processes such as proliferation, differentiation, and survival. Researchers utilize AG-1478 to investigate its effects on cancer cell lines, as EGFR signaling is often dysregulated in various types of cancers. By inhibiting EGFR, AG-1478 helps in understanding the mechanisms of tumor growth and in evaluating potential therapeutic strategies. Additionally, it is employed in studies related to wound healing and tissue regeneration, where EGFR signaling plays a critical role. Its application extends to neuroscience research, where it is used to explore EGFR's involvement in neuronal development and function. Overall, AG-1478 serves as a crucial tool in biomedical research for dissecting EGFR-related pathways and their implications in health and disease.
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