AMG 487
≥99%
- Product Code: 99534
CAS:
473719-41-4
| Molecular Weight: | 603.59 g./mol | Molecular Formula: | C₃₂H₂₈F₃N₅O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
AMG 487 is primarily investigated for its potential therapeutic applications in the field of immunology and inflammatory diseases. It functions as a selective antagonist of the CXCR3 receptor, which plays a crucial role in the migration of T cells to sites of inflammation. By blocking this receptor, AMG 487 can potentially inhibit the recruitment of inflammatory cells, making it a promising candidate for treating autoimmune diseases such as rheumatoid arthritis and psoriasis. Additionally, its mechanism of action has been explored in the context of transplant rejection, where it may help reduce immune-mediated damage to transplanted organs. Research is ongoing to further understand its efficacy and safety in clinical settings.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | solid |
| PURITY | 98.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.002 | 10-20 days | ฿5,280.00 |
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| 0.005 | 10-20 days | ฿7,300.00 |
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| 0.025 | 10-20 days | ฿23,410.00 |
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| 0.100 | 10-20 days | ฿59,730.00 |
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AMG 487
AMG 487 is primarily investigated for its potential therapeutic applications in the field of immunology and inflammatory diseases. It functions as a selective antagonist of the CXCR3 receptor, which plays a crucial role in the migration of T cells to sites of inflammation. By blocking this receptor, AMG 487 can potentially inhibit the recruitment of inflammatory cells, making it a promising candidate for treating autoimmune diseases such as rheumatoid arthritis and psoriasis. Additionally, its mechanism of action has been explored in the context of transplant rejection, where it may help reduce immune-mediated damage to transplanted organs. Research is ongoing to further understand its efficacy and safety in clinical settings.
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