ASP-9521

>98%

  • Product Code: 99555
  CAS:    1126084-37-4
Molecular Weight: 330.42 g./mol Molecular Formula: C₁₉H₂₆N₂O₃
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20℃
Product Description: ASP-9521 is primarily investigated for its potential application in the treatment of cancer, particularly prostate cancer. It functions as an androgen synthesis inhibitor, targeting the enzyme 17β-hydroxysteroid dehydrogenase type 5 (HSD17B5), which plays a crucial role in the production of androgens. By inhibiting this enzyme, ASP-9521 reduces the levels of active androgens, such as testosterone and dihydrotestosterone, which are known to drive the growth of androgen-dependent prostate cancer. This mechanism makes it a promising candidate for therapeutic use in patients with castration-resistant prostate cancer (CRPC), where traditional androgen deprivation therapies have become less effective. Clinical studies are ongoing to evaluate its efficacy, safety, and potential as part of combination therapies in oncology.
Product Specification:
Test Specification
APPEARANCE White to yellow to brown powder or crystals
PURITY 98-100
Infrared spectrum Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days ฿5,100.00
+
-
0.010 10-20 days ฿8,200.00
+
-
0.050 10-20 days ฿31,900.00
+
-
0.100 10-20 days ฿49,050.00
+
-
ASP-9521
ASP-9521 is primarily investigated for its potential application in the treatment of cancer, particularly prostate cancer. It functions as an androgen synthesis inhibitor, targeting the enzyme 17β-hydroxysteroid dehydrogenase type 5 (HSD17B5), which plays a crucial role in the production of androgens. By inhibiting this enzyme, ASP-9521 reduces the levels of active androgens, such as testosterone and dihydrotestosterone, which are known to drive the growth of androgen-dependent prostate cancer. This mechanism makes it a promising candidate for therapeutic use in patients with castration-resistant prostate cancer (CRPC), where traditional androgen deprivation therapies have become less effective. Clinical studies are ongoing to evaluate its efficacy, safety, and potential as part of combination therapies in oncology.
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