Bafetinib (INNO-406)
98%
- Product Code: 99717
CAS:
859212-16-1
| Molecular Weight: | 576.62 g./mol | Molecular Formula: | C₃₀H₃₁F₃N₈O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18633200 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
Bafetinib is primarily utilized in the field of oncology, particularly for the treatment of certain types of leukemia. It functions as a potent inhibitor of Bcr-Abl tyrosine kinase, which is implicated in the pathogenesis of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). By targeting this kinase, bafetinib helps to impede the proliferation of leukemic cells, thereby offering a therapeutic option for patients who may have developed resistance to other tyrosine kinase inhibitors. Additionally, its ability to cross the blood-brain barrier makes it a potential candidate for addressing central nervous system involvement in these malignancies. Ongoing research continues to explore its efficacy and potential applications in other cancer types.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Light yellow to yellow Solid |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿3,290.00 |
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| 0.025 | 10-20 days | ฿11,320.00 |
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Bafetinib (INNO-406)
Bafetinib is primarily utilized in the field of oncology, particularly for the treatment of certain types of leukemia. It functions as a potent inhibitor of Bcr-Abl tyrosine kinase, which is implicated in the pathogenesis of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). By targeting this kinase, bafetinib helps to impede the proliferation of leukemic cells, thereby offering a therapeutic option for patients who may have developed resistance to other tyrosine kinase inhibitors. Additionally, its ability to cross the blood-brain barrier makes it a potential candidate for addressing central nervous system involvement in these malignancies. Ongoing research continues to explore its efficacy and potential applications in other cancer types.
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