BCR-ABL-IN-1
98%
- Product Code: 99786
CAS:
188260-50-6
| Molecular Weight: | 459.44 g./mol | Molecular Formula: | C₂₃H₂₁F₄N₅O |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
BCR-ABL-IN-1 is primarily used in research settings to study its inhibitory effects on the BCR-ABL fusion protein, which is associated with chronic myeloid leukemia (CML). It serves as a tool compound to investigate the mechanisms of BCR-ABL-driven oncogenesis and to explore potential therapeutic strategies for CML. Researchers utilize it to evaluate its efficacy in blocking the tyrosine kinase activity of BCR-ABL, which is crucial for the proliferation of leukemia cells. Additionally, it aids in understanding resistance mechanisms to existing BCR-ABL inhibitors and in developing next-generation targeted therapies. Its application extends to preclinical studies, where it helps assess pharmacokinetics, pharmacodynamics, and safety profiles in cellular and animal models.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
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| 0.001 | 10-20 days | Ft1,153,260.52 |
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| 0.005 | 10-20 days | Ft1,844,742.77 |
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BCR-ABL-IN-1
BCR-ABL-IN-1 is primarily used in research settings to study its inhibitory effects on the BCR-ABL fusion protein, which is associated with chronic myeloid leukemia (CML). It serves as a tool compound to investigate the mechanisms of BCR-ABL-driven oncogenesis and to explore potential therapeutic strategies for CML. Researchers utilize it to evaluate its efficacy in blocking the tyrosine kinase activity of BCR-ABL, which is crucial for the proliferation of leukemia cells. Additionally, it aids in understanding resistance mechanisms to existing BCR-ABL inhibitors and in developing next-generation targeted therapies. Its application extends to preclinical studies, where it helps assess pharmacokinetics, pharmacodynamics, and safety profiles in cellular and animal models.
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