Vitamin E Calcium Succinate

  • Product Code: 127597

a stable ester form of vitamin E with properties different from alpha-tocopherol or alpha-tocopheryl acetate.

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What is Vitamin E Calcium Succinate?
Vitamin E Calcium Succinate is a compound combining:

  • Vitamin E (as Alpha-Tocopheryl Succinate) – a stable ester form of vitamin E with properties different from alpha-tocopherol or alpha-tocopheryl acetate.

  • Calcium – an essential mineral.

  • Succinate (Succinic Acid) – a metabolic intermediate in the Krebs cycle (energy production in cells).

While each component has established benefits, the combined salt form primarily serves as a delivery system. There is limited research indicating unique synergistic effects beyond delivering vitamin E and calcium together.


Potential Health Benefits & Supporting Research

1. Vitamin E Benefits (Alpha-Tocopheryl Succinate - VES)

  • Antioxidant (Indirect Effect):
    VES itself is not a strong antioxidant, but once hydrolyzed in the body, it releases alpha-tocopherol, a potent fat-soluble antioxidant that protects cells from oxidative damage.

    • Traber MG & Atkinson J. (2007). Free Radical Biology and Medicine, 43(1), 4–15.

  • Anti-Cancer Potential (Preclinical Evidence):
    VES has been studied for its ability to induce apoptosis (cell death), reduce proliferation, and block angiogenesis in cancer cells.

    • Shiau CW et al. (2013). J Cell Physiol, 228(4), 764–772.

    • Neuzil J et al. (2001). Apoptosis, 6(1–2), 31–47.

    Note: These are preclinical studies. There’s no clinical proof yet that VES can treat or prevent cancer in humans.

  • Immune Modulation:
    Vitamin E may support immune function. This is well-established for alpha-tocopherol; data on VES is limited.


2. Calcium Benefits

  • Bone Health: Supports strong bones and teeth, and helps prevent osteoporosis.

    • Institute of Medicine (2011). Dietary Reference Intakes for Calcium and Vitamin D.

  • Muscle Function & Nerve Transmission

  • Blood Clotting: Required for normal coagulation.


3. Succinate (Succinic Acid) Role

  • Energy Metabolism: As part of the Krebs cycle, succinate contributes to energy production. However, supplementation doesn’t necessarily enhance energy in healthy individuals.




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Vitamin E Calcium Succinate

a stable ester form of vitamin E with properties different from alpha-tocopherol or alpha-tocopheryl acetate.

What is Vitamin E Calcium Succinate?
Vitamin E Calcium Succinate is a compound combining:

  • Vitamin E (as Alpha-Tocopheryl Succinate) – a stable ester form of vitamin E with properties different from alpha-tocopherol or alpha-tocopheryl acetate.

  • Calcium – an essential mineral.

  • Succinate (Succinic Acid) – a metabolic intermediate in the Krebs cycle (energy production in cells).

While each component has established benefits, the combined salt form primarily serves as a delivery system. There is limited research indicating unique synergistic effects beyond delivering vitamin E and calcium together.


Potential Health Benefits & Supporting Research

1. Vitamin E Benefits (Alpha-Tocopheryl Succinate - VES)

  • Antioxidant (Indirect Effect):
    VES itself is not a strong antioxidant, but once hydrolyzed in the body, it releases alpha-tocopherol, a potent fat-soluble antioxidant that protects cells from oxidative damage.

    • Traber MG & Atkinson J. (2007). Free Radical Biology and Medicine, 43(1), 4–15.

  • Anti-Cancer Potential (Preclinical Evidence):
    VES has been studied for its ability to induce apoptosis (cell death), reduce proliferation, and block angiogenesis in cancer cells.

    • Shiau CW et al. (2013). J Cell Physiol, 228(4), 764–772.

    • Neuzil J et al. (2001). Apoptosis, 6(1–2), 31–47.

    Note: These are preclinical studies. There’s no clinical proof yet that VES can treat or prevent cancer in humans.

  • Immune Modulation:
    Vitamin E may support immune function. This is well-established for alpha-tocopherol; data on VES is limited.


2. Calcium Benefits

  • Bone Health: Supports strong bones and teeth, and helps prevent osteoporosis.

    • Institute of Medicine (2011). Dietary Reference Intakes for Calcium and Vitamin D.

  • Muscle Function & Nerve Transmission

  • Blood Clotting: Required for normal coagulation.


3. Succinate (Succinic Acid) Role

  • Energy Metabolism: As part of the Krebs cycle, succinate contributes to energy production. However, supplementation doesn’t necessarily enhance energy in healthy individuals.

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