Deoxyarbutin (D-Arbutin)
Analytical
Code: 1298
High efficiency in whitening compared to Arbutin, Alpha Arbutin, Kojic Acid, Hydroquinone.
*Can irritate the skin*
(Thailand FDA no longer allow this ingredient to be used in the cosmetics - check your local FDA before purchasing)
Deoxyarbutin or D-Arbutin has high whitening efficiency compared to Arbutin, Alpha Arbutin, Kojic Acid, Hydroquinone.
From the experiment comparing Tysosinase Activity Inhibition, it was found that Deoxyarbutin (dA) inhibits Tyrosynase or melanin production better than Arbutin, Kojic Acid, and Hydroquinone.
from making Western blot found Deoxyarbutin It inhibits Tyrosinase better than Hydroquinone, 8-methoxypsoralen and Arbutin.
Lab experiments also found that Deoxyarbutin As an antioxidant, it can help reduce ROS (reactive oxygen species).
from safety trials with photographic measurements Viability/morphology of human fibroblasts and keratinocytes showed that Hydroquinone and DMSO were more virulent to cells than dA (D-Arbutin, Deoxyarbutin ) by showing less white space.
Although the experiment above shows that Deoxyarbutin Less irritating to the skin than Hydroquinone and DMSO, but experiments have confirmed that. Deoxyarbutin Can irritate the skin significantly. Please avoid using on sensitive skin. or irritated skin and do not use more than the rate specified by the manufacturer at 2.0%
Instructions in the formula for which Deoxyarbutin is used
1. Deoxyarbutin soluble in oil By using heat about 50-60 degrees to help melt. Please avoid heating above 60 degrees. If necessary, please shorten the time to a minimum. to prevent Deoxyarbutin loses its quality
2. The formula should be used ActiveProtec™ OX at 0.6% to help prevent formula discoloration.
3. Using Vitamin E Acetate The 0.1% rate in the formula can help Deoxyarbutin is more stable.
4. The formula should have a pH in the range of 5.0-5.8, which is the best pH level for its stability. Deoxyarbutin
Warning
1. At present, there are no independent research findings confirming that Deoxy-arbutin It is more effective in whitening than Alpha. Arbutin, in its internal trials, has shown that it only works better in some users.
2. From the chemical structure of Deoxy-arbutin Can irritate the skin. Please try starting at low level.
Use: For whitening products to brighten the skin in the form of lotion or cream (recommended for at least 8 weeks in a row, results vary from person to person).
Mixing method: mix in the oil by avoiding heat over 60 °C The formula should have a pH between 5.0-5.8.
Usage rate: 0.5-2% (recommended 0.5% for whitening to brighten the skin. Do not use more than 2.00% due to skin irritation, found that using 1-2% can irritate the skin)
Product characteristics: pure white powder
Solubility: can be dissolved in oil and Alcohol
INCI Name : Deoxyarbutin
- Frozen (<0C)
- 24 Months from manufacturing or testing date.
- Add at last step. Avoid temperature above 40C.
- Avoid heat above 60C
- 5.00 - 5.80
- Soluble in Oil, Soluble in Ethanol
- Cream, Lotion, Mask
- -
| Test Name | Specification |
|---|---|
| Appearance | Off-white crystalline powder |
| Assay | 98.0% Min |
| Melting point | 84~88C |
| Clarity of alcohol solution | Transparency, colorless, none suspended matters |
| Arsenic | 2ppm Max |
| Heavy Metals | 10ppm Max |
| Loss on drying | 0.5% Max |
| Ignition residue | 0.5% Max |
| Bacteria count | 300CFU/g Max |
| Fungus count | 100CFU/g Max |