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Is there any research for Epidermal Growth Factor (EGF, Recombinant)?
I’d like a formula for a body oil that is not sticky or greasy, using natural oils to help make the skin look bright + moisturized. Questions: - Can essential oil be mixed in directly? - Or do I need to use an emulsifier to help everything blend together? I want to make it as a gift for a friend within this week.
So Phospholipid (Hydrogenated Lecithin) is dispersible in water? It says the product must contain an oil phase. I need hydrogenated Lecithin to create ethosomes with ethanol, but I am not sure which of the many products might be suitable. Could you please help? Thank you in advance!
Hello, Recently, I experimented with Glyceryl Stearate Citrate (GSC) as an O/W emulsifier. I heated both phases to 75°C, but upon initial mixing with an electric mixer, the mixture appeared to curdle immediately, suggesting a failed emulsification. However, I continued to mix. After one minute, I switched to manual stirring. Within two minutes, the cream began to homogenize but developed a gluey, slime-like consistency. After another two minutes, this 'slime' suddenly liquefied. Once I added the gum-humectant slurry during the cool-down phase, the emulsion regained some viscosity and ultimately appeared homogenous. Are these phase transitions and observations normal for GSC? Is this emulsifier widely used in natural skincare? While I appreciate the light skin feel, I need the emulsification process to be more reliable and predictable. I have not encountered this type of behavior with other emulsifiers, so I would highly appreciate your insights and any advice on proper processing techniques. Additional details: - Oil phase at 13% (different oils and esters) - Xanthan Gum (and) Lecithin (and) Sclerotium Gum (and) Pullulan at 0.5% - Glycerine at 5% - Water phase (distilled water and phytic acid) - No electrolytes - final pH= 5.2 - batch size: 50g - mixing with high speed mixer - heating to 75 degrees Celsius, then cooling while mixing manually - Glyceryl Stearate Citrate at 3% - Dicaprylyl Carbonate and Isoamyl Laurate are the main components of oil phase,, GSC is not included in 13% Thanks!
Hello, Currently, I have a sunscreen formula as attached. The client wants to adjust it into a “Foundation Sunscreen” that can serve as a makeup base, while incorporating a more “Reef Friendly / Coral Friendly” concept. **Current Formula:** **Part A** * Water — 42.45% * Disodium EDTA — 0.20% * Butylene Glycol — 0.20% **Part B** * Ethylhexyl Salicylate — 5.00% * Titanium Dioxide Transparent — 5.00% * Ethylhexyl Triazone — 4.00% * LipidSoft™ Lite — 5.00% * Aqua EMU 2217 — 2.00% **Part C** * Multicare MP40KC — 5.00% **Part D** * Water — 5.00% * Allantoin — 0.20% * Niacinamide — 1.00% **Part E** * Extract — 0.25% **Part F** * Water — 2.00% * Isododecane — 2.00% * AminoSil™ (Lauroyl Lysine) — 2.60% * Sicare 2215 — 2.60% (Thinking of using SiliSolve™ instead) * Sicare 9900 — 15.00% **Part G** * Microcare PEHG — 0.50% **Questions for MySkinRecipes:** 1. From the current formula, can I use only ReadyMix™ Beige Iron Oxides (Isononyl Isononanoate Based) to create the foundation shade? If used alone, will it provide sufficient coverage and color stability, or should I mix additional Iron Oxides to balance the skin tone? 2. If I want to add the following nourishing ingredients, can they be included in the formula, and at what percentage? * Aloe Vera Extract * Vitamin B3 (Niacinamide) * Hyaluronic Acid 3. In the current formula, are there any ingredients that should be adjusted, reduced, or changed to make the formula: * More Reef Friendly * Easier to spread * Reduce creasing/streaking * More suitable as a foundation sunscreen 4. If I want the formula to have good SPF Protection with a lightweight feel, does MySkin have additional advice on: * Silicone balance * Pigment dispersion * Emulsifier * Film former * Or other ingredients? Please also provide guidance on the formulation process. Thank you very much.
Do you know what the approximate shikonin content is in Lithospermum Erythrorhizon Root Powder (Murasaki Powder)? * What is the powder base? * Will the product appear hazy when dispersed in water or glycol?
What does "can emulsify up to 20% oil" mean? For example, if I use 1g of **Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer**, does it mean I can have a ratio of 20g of oil? Please explain.
I am trying to make a homemade powder laundry detergent that has a very heavy scent throw after washing. I’m air drying to preserve the scent. Everything I tried is not locking the scent onto the clothes. How would this benefit in a diy powder recipe or willing to change to liquid if it actually work. Thanks! I’ve used everything from the standard diy grated soap recipe to using one with Sls powder. My most current recipe used: * 45 g baking soda * 5 g washing soda * 10 g sodium citrate * 19 g Epsom salt * 20 g natrasorb * 6 g cyclodextrin * 15 g fragrance oil (comes out a 6% strength)
สอบถามเปรียบเทียบสารรายการดังนี้ ลงในสูตรแชมพู 1.Silicone Micro-Cond 2.Hair-cond SM 3.Hair-cond XL 4.HairSoft843 ตัวไหนให้ความนุ่มลื่นแก่เส้มผมได้ดี ทั้งตอนผมเปียก และผมแห้ง
Please recommend a clear, non-sticky gelling agent for a body gel with the following specifications: * **Ingredients:** Contains approximately 20% various extracts * **Formulation:** No salt * **Viscosity:** Serum level
Hello. I would like to inquire about fragrance fixatives for a shampoo formulation. * **Primary Surfactant:** Sodium C14-16 Olefin Sulfonate
About the Peptide testing. If I give you 1 vial, are you able to take a sample from it and give me it back? Or do I lose the complete vial? I would be interested in a Full test. The vials contain between 5mg - 10mg.
I would like to place a production order, but I am unable to do so because some ingredients in my formula are no longer available. I need to adjust the formula to proceed with production. **Booster Lifting and Regenerating Serum** **Ingredients:** * Salmon DNA (PDRN, Polydeoxyribonucleotide, 5000ppm Solution): 12.00% * Super-HYA™ (Sodium Acetylated Hyaluronate, AcHA): 0.10% * 8D Hyaluronic Acid: 10.00% * BEE-TOX™ (100ppm Melittin Bee Venom Solution): 8.00% * Repair Activator™ Powder (Bifida Ferment Lysate): 1.00% *(Discontinued)* * Pro-Xylane (Hydroxypropyl Tetrahydropyrantriol, Liquid): 2.00% * Ethylbisiminomethylguaiacol Manganese Chloride: 0.05% * Retinal-EZ™ (Encapsulated Water Dispersible Retinal): 5.00% * Pure-Adenosine™: 0.50% * Quick-Coll®: 2.00% *(Discontinued)* * Pep-Calm™ (Palmitoyl Tripeptide-8): 2.50% * Tranexamic Acid (Trans-White™): 3.00% * Safe-B3™ (Vitamin B3, Niacinamide, Switzerland): 8.00% * GlucoBright™ (Acetyl Glucosamine): 4.00% * Tocotrienols (Oil, 50%, Cosmetics): 1.00% * Panthenol (Vitamin B5, DL-Panthenol, Powder): 0.50% * Kukui Nut Oil: 2.00% * Shea Butter (Melt): 2.00% * ActiveProtec™ OX: 1.00% * LipidSoft™ Moist (Triethylhexanoin): 2.00% * Dimethyl Isosorbide (DMI): 3.00% * LecithinGel™: 2.50% * Jeju Camellia (compare to Organist): 0.50% *(Discontinued)* * Mild Preserved Eco™ (Preservative-Free): 1.00% * Purified Water (TDS Limit 1ppm): 25.35% * Methylsilanol Mannuronate: 1.00% * **Total: 100.00%** Can I use the following ingredients as replacements, or what would you recommend for this formula? * Use **Black Sea Moss Extract** (Hydrolyzed Rhodophyceae extract) 1% to replace Repair Activator™ Powder. * Use **VoluLift™** (Palmitoyl Isoleucine) 1.5% to replace Quick-Coll®. * Use **Tuberose Fragrance Oil** 0.5% to replace Jeju Camellia (or another suitable fragrance for a serum as the research team sees fit). * What if I add **Spilanthol Expression Liposome** (Natural Botox, Spilanthol 1.5% Water Soluble) 0.5% or 1% and reduce the water content to maintain the 100% ratio? Additionally, please help adjust the formula to reduce color changes. When left at room temperature for 2-4 weeks, the product turns from light yellow to brown and develops a small amount of sediment. Please feel free to adjust the ingredients as the research team sees fit. After the formula is updated, what parameters should be tested (e.g., pH, clarity over time, or wrinkle reduction)? And how should I proceed with the new production order and testing fees?
I would like to modify my serum formula because some ingredients are no longer available. I want to make the following changes: * Use **Black Sea Moss Extract (Hydrolyzed Rhodophyceae extract) 1%** to replace **Repair Activator™ Powder (Bifida Ferment Lysate)** * Use **VoluLift™ (Palmitoyl Isoleucine) 1.5%** to replace **Quick-Coll®** * Use **Tuberose Fragrance Oil 0.5%** to replace **Jeju Camellia (compare to Organist)** * Add **Spilanthol Expression Liposome (Natural Botox, Spilanthol 1.5% Water Soluble) 0.5% or 1%** and reduce the water content to balance the formula to 100%. Also, I need advice regarding the product's color changing from light yellow to brown after being left at room temperature for about 1 month. Do I need to add any specific ingredients to prevent this? **Current Formula: Booster Lifting and Regenerating Serum** * Salmon DNA (PDRN, Polydeoxyribonucleotide, 5000ppm Solution) 12.00% * Super-HYA™ (Sodium Acetylated Hyaluronate, AcHA) 0.10% * 8D Hyaluronic Acid 10.00% * BEE-TOX™ (100ppm Melittin Bee Venom Solution) 8.00% * Repair Activator™ Powder (Bifida Ferment Lysate) 1.00% * Pro-Xylane (Hydroxypropyl Tetrahydropyrantriol, Liquid) 2.00% * Ethylbisiminomethylguaiacol Manganese Chloride 0.05% * Retinal-EZ™ (Encapsulated Water Dispersible Retinal) 5.00% * Pure-Adenosine™ 0.50% * Quick-Coll® 2.00% * Pep-Calm™ (Palmitoyl Tripeptide-8) 2.50% * Tranexamic Acid (Trans-White™) 3.00% * Safe-B3™ (Vitamin B3, Niacinamide, Switzerland) 8.00% * GlucoBright™ (Acetyl Glucosamine) 4.00% * Tocotrienols (Oil, 50%, Cosmetics) 1.00% * Panthenol (Vitamin B5, DL-Panthenol, Powder) 0.50% * Kukui Nut Oil 2.00% * Shea Butter (Melt) 2.00% * ActiveProtec™ OX 1.00% * LipidSoft™ Moist (Triethylhexanoin) 2.00% * Dimethyl Isosorbide (DMI) 3.00% * LecithinGel™ 2.50% * Jeju Camellia (compare to Organist) 0.50% * Mild Preserved Eco™ (Preservative-Free) 1.00% * Purified Water (TDS Limit 1ppm) 25.35% * Methylsilanol Mannuronate 1.00% * **Total = 100%**
Please provide detailed instructions for using Iron Oxides EasyMix. I tried using them in a foundation sunscreen formula, but the black pigment settled, and there were red streaks in the beaker when stirring. I would like advice on: * What can these pigments be dissolved in? * Is a homogenizer required? If so, what speed should be used? * Recommendations for the ingredient percentages and the process for creating the foundation sunscreen. * How to improve pigment dispersion, as my current trial separated and had black sediment after centrifuging. **Current Formula (W/O):** **Part A** * Water: 41.20% * Disodium EDTA: 0.2% * Glycereth-26: 0.5% * Butylene glycol: 1% * Carbopol Ultrez 21: 0.2% * TEA: 0.2% **Part B** * Uvinul A Plus Granular: 3.5% * Uvinul T 150: 2.5% * C12-15 Alkyl Benzoate: 4% * Lipidsoft lite: 2% * Milk lotion maker: 3.5% * Cutina GMS SE: 1% * Eumulgin B2: 2.5% * BHT: 0.2% * Foundation Color: 0.5% (Yellow Iron Oxides EasyMix™: 83.5%, Red Iron Oxides EasyMix™: 13.7%, Black Iron Oxides EasyMix™: 2.8%) **Part C** * Tinosorb A2B: 5% **Part D** * Sicare 2955: 8% * KSP-100: 5% * Mirasil Cetyl DM: 3% **Part D (Repeated in original)** * CreamMaker EG: 2% **Part F** * Water: 5% * Niacinamide: 3% * Double Hyaluron Liquid: 0.5% * Aloe Vera Extract: 0.5% * Natural Extract: 1% **Part G** * Fragrance: 0.5% * Phenoxyethanol & Ethylhexylglycerin: 1%
Will you help me formulate a luxy lipstick with luxury esters? I would like to make a modern luxury lipstick which is long lasting, matte (but not too matte) but moisturising. I want it to feel luxurious. I have a number of ingredients, but i want to know from a starting point what someone would suggest. Here are my ingredients: * BDPA-2 (Vegan Lanolin) * Diisostearyl Malate * Hydrogenated Polyisobutene * Olive Squalane * Isododecane * Jojoba Oil * Castor Oil * Sweet Almond Oil * Lanolin (natural) * Beeswax * Candelilla Wax * Carnauba Wax * Murumuru Butter * Illipe Butter * Shea Butter * Cocoa Butter * Trimethylsiloxysilicate (Flake Resin) * Silica Microspheres * Magnesium Stearate * Red 7 Lake * Red 27 Lake * Blue Lake * Iron Oxides * Titanium Dioxide * Synthetic Fluorphlogopite * Micas (various) * Flavour Oils * Vitamin E * Versagel ME 750 * Isopropyl Alcohol * Tridecyl Trimellitate (TDTM) * Lecithin * Dimethicone * Dimethicone Crosspolymer * Polyamide-3 * Isostearyl Neopentanoate * Diisopropyl Sebacate * C12-15 Alkyl Benzoate * Triisostearyl Citrate * microcrystalline wax I want to make a bullet lipstick.
I have a project to make a dog shampoo. Which active ingredients would you recommend for reducing itching?
In the case of using Sodium Fluoride (anti-caries, oral care) in toothpaste to claim a concentration of 1500 ppm, can this be calculated back into a percentage to determine how many % to use? P.S. The law states it must not exceed 0.15%.
I need formulas for the following: * Roll-on Antiperspirant (clear and white formulas) * Deodorant cream and antiperspirant cream * Toothpaste Requirements: * **Toothpaste:** Whitening, for sensitive teeth, and fluoride-based. * **Antiperspirants and Deodorants:** Quick-drying and 72-hour effective.
1. What are the suitable containers and batch sizes for mixing skincare products throughout the process, from formulation development and initial testing to stability testing? 2. After mixing the formula, is it necessary to let the product rest for 1 night? Should measurements be taken before or after resting, or should they be repeated, and how?
