Lys-Nε-SPDB-DM4
≥98%
Reagent
Code: #108790
CAS Number
1280215-91-9
blur_circular Chemical Specifications
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Molecular Information
Weight
1026.69 g/mol
Formula
C₄₈H₇₂ClN₅O₁₃S₂
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used primarily in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It serves as a linker-payload, connecting cytotoxic agents to monoclonal antibodies, enabling precise delivery of the drug to cancer cells while minimizing damage to healthy tissues. This enhances the therapeutic efficacy and reduces systemic toxicity. It is particularly valuable in treating cancers with specific antigen expression, such as certain types of breast, lung, and hematologic malignancies. Its stability and efficient release of the cytotoxic payload within the target cells make it a critical component in advanced oncology treatments.
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