Used primarily in research settings to study steroid hormone receptors, particularly the mineralocorticoid receptor. It serves as a reference compound for evaluating receptor selectivity and antagonistic activity due to its structural similarity to spironolactone but with improved specificity. Often employed in biochemical assays to differentiate mineralocorticoid-mediated effects from other steroid pathways. Also used in metabolic stability studies and drug metabolism research because of its susceptibility to enzymatic modification at the 7β position.