Used in neuroscience and Alzheimer’s disease research to quantify γ-secretase activity in biological samples. Enables detection of amyloid-beta peptide production, helping study the pathogenesis of Alzheimer’s and evaluate potential therapeutic compounds. Widely applied in preclinical drug development to assess inhibitors or modulators of γ-secretase function. Suitable for cell lysates, tissue homogenates, and conditioned media from neuronal cultures. Provides a reliable, high-throughput method for monitoring enzyme activity and screening drug candidates targeting amyloid precursor protein processing.