Used primarily in histology to visualize elastic fibers in tissue sections, especially in skin, blood vessels, and lung tissues. The stain helps pathologists assess the integrity and distribution of elastic fibers, which is critical in diagnosing conditions such as emphysema, arterial sclerosis, and connective tissue disorders. It is commonly applied in research and clinical settings to evaluate tissue architecture and structural changes in diseases affecting the extracellular matrix. The Verhöeff method provides high contrast and specificity, making it ideal for detailed microscopic examination.