Used in research to measure soluble α-klotho protein levels in biological samples such as serum, plasma, and cell culture supernatants. Enables scientists to study the role of α-klotho in aging, kidney disease, cardiovascular conditions, and metabolic disorders. Commonly applied in preclinical studies and biomarker validation to assess disease progression and response to treatment. Supports investigations into age-related decline and potential therapeutic interventions targeting the klotho pathway.