β-Amyloid Peptide (1-42) (rat/mouse) TFA
TFA salt, 95%
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Widely used in neuroscience research to model and study the molecular mechanisms of Alzheimer’s disease. It is particularly valuable for investigating amyloid plaque formation, as this peptide is a major component of such plaques in the brains of affected individuals. Researchers apply it in cell culture and animal models to induce neurotoxicity, synaptic dysfunction, and inflammation—hallmarks of neurodegenerative processes. Its aggregation behavior is studied to screen potential therapeutic compounds that inhibit or reverse fibril formation. Commonly used in assays measuring oxidative stress, mitochondrial dysfunction, and neuronal death. Also employed in drug development and validation of imaging agents targeting amyloid deposits.
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