Azidotrimethyltin(IV) is primarily utilized in organic synthesis as a reagent for introducing azide groups into various compounds. Its application is significant in the preparation of azido derivatives, which are intermediates in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The compound is also employed in click chemistry reactions, particularly in the formation of triazoles, which are valuable in drug discovery and material science. Additionally, it serves as a precursor in the development of organotin compounds, which have applications in catalysis and polymer stabilization. Its reactivity and stability make it a useful tool in specialized chemical transformations.