HIF-1 alpha (556-574) is a peptide fragment derived from the hypoxia-inducible factor 1-alpha, which plays a critical role in cellular responses to low oxygen levels. This specific fragment is often utilized in research to study the mechanisms of hypoxia and its effects on cellular processes. It is particularly valuable in understanding how cells adapt to oxygen deprivation, which is relevant in conditions like cancer, ischemic diseases, and stroke. Researchers use this peptide to investigate the signaling pathways involved in angiogenesis, metabolism, and cell survival under hypoxic conditions. Additionally, it serves as a tool in drug development, helping to identify potential therapeutic targets for diseases where hypoxia is a key factor. Its application extends to studying the regulation of gene expression in response to oxygen levels, providing insights into the molecular basis of hypoxia-related disorders.