Franz Cell Analysis (Porcine Ear, 6 samples, 1 Time Point)
- Product Code: 11135
Skin permeability analysis service with Franz Cell using 6 month old pig ear skin.
Suitable for water-soluble actives
description Service Overview
Franz Cell Analysis (Porcine Ear, 6 sample)
Skin permeability analysis service with Franz Cell using 6 month old pig ear skin.
Price per 6 samples. This price does not include measurement of permeate substances (can choose to use HPLC or UV VIS).
The sample must be in liquid form.
Use at least 20 grams of sample.
Duration: 1 week for making Franz Cell, not including measurement period (HPLC 5 days, UV VIS 2 days)
timeline Service Steps
| Step | Procedure | Expected Result |
|---|---|---|
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1
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Prepare pH... |
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pH 7.4 buffer solution ready for use. |
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2
|
Obtain and... |
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Preserved porcine skin that can be thawed and used when needed. |
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3
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Soak porcine... |
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Hydrated porcine skin ready for permeation testing. |
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4
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Prepare test... |
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A 1% Vitamin C test solution ready for application to the donor compartment. |
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5
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Assemble and... |
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Stable and consistent test environment that mimics skin temperature and ensures uniform mixing. |
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6
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Apply the... |
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Start of permeation study, with Vitamin C contacting the skin surface. |
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7
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Collect receptor... |
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Timed aliquots that represent permeated Vitamin C concentration. |
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8
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Sample dilution... |
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Uniformly diluted samples ready for UV-Vis measurement. |
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9
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Measure absorbance... |
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Accurate absorbance readings corresponding to the Vitamin C concentration in each sample. |
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10
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Calculate Vitamin... |
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Quantitative determination of Vitamin C permeation through the skin over time. |
You will receive a report for the % cumulative release and µg outlet cumulative release fields when we provide this service
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