Fmoc-Thr(Ac4Manα1-2Ac3Manα)-OH
≥95%
Reagent
Code: #186770
CAS Number
482576-73-8
science Other reagents with same CAS 482576-73-8
blur_circular Chemical Specifications
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Molecular Information
Weight
959.9 g/mol
Formula
C₄₅H₅₃NO₂₂
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Storage & Handling
Storage
-20°C, sealed, light-proof
description Product Description
Used in the synthesis of glycopeptide-based vaccines and immunological studies, this compound enables site-specific incorporation of a disaccharide motif found in certain bacterial cell walls, particularly in Mycobacterium tuberculosis. The Fmoc group allows for solid-phase peptide synthesis using standard Fmoc-tactics, making it suitable for automated peptide assembly. The acetylated mannose disaccharide (Ac4Manα1-2Ac3Manα) mimics natural epitopes involved in immune recognition, facilitating the development of synthetic antigens for diagnostic or vaccine design. Its application is primarily in research settings focused on carbohydrate-mediated immune responses and the construction of complex glycoconjugates for tuberculosis and other infectious disease targets.