Used in neuroscience and biomedical research to detect and quantify oligomeric forms of α-synuclein in biological samples such as cerebrospinal fluid, plasma, or tissue lysates. Plays a critical role in studies related to Parkinson’s disease and other synucleinopathies, where α-synuclein oligomers are considered toxic species involved in disease progression. Enables researchers to monitor changes in oligomer levels in response to experimental treatments, aiding in the development of potential therapeutics. Provides a reliable, sensitive, and specific method for early diagnosis, biomarker validation, and mechanistic studies in neurodegenerative disease models.