Used primarily as an active metabolite in hormonal contraception and hormone replacement therapies. It contributes to the progestogenic activity of levonorgestrel-based contraceptives by binding to progesterone receptors, helping suppress ovulation and modify the endometrium to prevent pregnancy. Also involved in the regulation of menstrual cycles and studied for its role in metabolic pathways related to steroid hormones. Its presence in the body affects the overall efficacy and duration of action of contraceptive formulations.