2-[4-(Fluorosulfonyl)phenyl]acetic acid

95%

  • Product Code: 130688
  CAS:    402-57-3
Molecular Weight: 218.2 g./mol Molecular Formula: C₈H₇FO₄S
EC Number: MDL Number: MFCD24483006
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, Sealed, Inert Gas
Product Description: Used primarily as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of anti-inflammatory and antidiabetic agents. Its fluorosulfonyl group enables strong electron-withdrawing properties, making it valuable in constructing sulfonamide and sulfone derivatives through nucleophilic substitution reactions. It is also employed in the preparation of covalent inhibitors due to the reactivity of the sulfonyl fluoride moiety, which can selectively bind to specific amino acid residues in target proteins. Additionally, it finds use in material science for modifying polymer surfaces and enhancing chemical resistance through cross-linking reactions.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days £186.39
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0.250 10-20 days £316.05
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1.000 10-20 days £789.78
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2-[4-(Fluorosulfonyl)phenyl]acetic acid
Used primarily as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of anti-inflammatory and antidiabetic agents. Its fluorosulfonyl group enables strong electron-withdrawing properties, making it valuable in constructing sulfonamide and sulfone derivatives through nucleophilic substitution reactions. It is also employed in the preparation of covalent inhibitors due to the reactivity of the sulfonyl fluoride moiety, which can selectively bind to specific amino acid residues in target proteins. Additionally, it finds use in material science for modifying polymer surfaces and enhancing chemical resistance through cross-linking reactions.
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