Methyl 4-(1,3-dioxoisoindolin-2-yl)butanoate
95%
Reagent
Code: #212123
CAS Number
39739-03-2
science Other reagents with same CAS 39739-03-2
blur_circular Chemical Specifications
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Molecular Information
Weight
247.25 g/mol
Formula
C₁₃H₁₃NO₄
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as an intermediate in organic synthesis, particularly in the preparation of bioactive molecules and pharmaceuticals. Its structure contains a reactive isoindoline-dione moiety and an ester functional group, making it suitable for conjugation reactions and ring-forming transformations. Commonly employed in the development of proteolysis-targeting chimeras (PROTACs), where it serves as a linker component to connect target-binding ligands with E3 ubiquitin ligase recruiters. Also utilized in medicinal chemistry for building complex heterocyclic systems due to its ability to undergo nucleophilic substitution, hydrolysis, and reduction under controlled conditions.