(R)-1-(2-(Difluoromethoxy)-4-fluorophenyl)ethan-1-amine

97%

  • Product Code: 231947
  CAS:    1344954-03-5
Molecular Weight: 205.18 g./mol Molecular Formula: C₉H₁₀F₃NO
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used as a key chiral intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its stereochemistry enhances binding selectivity to neurotransmitter receptors, improving drug efficacy and reducing side effects. Also employed in the preparation of agrochemicals where chirality influences biological activity. The presence of fluorine atoms increases metabolic stability and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active ingredients.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.050 10-20 days ฿15,610.00
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0.100 10-20 days ฿24,960.00
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0.250 10-20 days ฿41,600.00
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0.500 10-20 days ฿73,650.00
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0.020 10-20 days ฿81,360.00
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(R)-1-(2-(Difluoromethoxy)-4-fluorophenyl)ethan-1-amine
Used as a key chiral intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its stereochemistry enhances binding selectivity to neurotransmitter receptors, improving drug efficacy and reducing side effects. Also employed in the preparation of agrochemicals where chirality influences biological activity. The presence of fluorine atoms increases metabolic stability and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active ingredients.
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