Ko143 hydrate
98%
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description Product Description
Ko143 hydrate is primarily used in research settings as a potent and selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2). It is extensively applied in studies focused on understanding drug resistance mechanisms in cancer therapy, particularly in overcoming multidrug resistance. Researchers utilize it to investigate the role of BCRP in the efflux of chemotherapeutic agents, which helps in developing strategies to enhance the efficacy of cancer treatments. Additionally, it is employed in pharmacokinetic studies to assess the impact of BCRP on drug absorption, distribution, and excretion. Its application also extends to stem cell research, where it aids in identifying and isolating stem cell populations based on BCRP expression.
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| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 98-100 |
| Appearance | White To Off-White Powder |
| Infrared Spectrometry | Conforms to Structure |
| Solubility | >10 mg/mL in DMSO |
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