Zofenopril is primarily used in the treatment of hypertension, helping to lower high blood pressure and reduce the risk of cardiovascular events. It is also effective in managing heart failure by improving cardiac function and reducing symptoms such as shortness of breath and fatigue. Additionally, it is prescribed after a heart attack to improve survival rates and prevent further heart damage. The medication works by relaxing blood vessels, allowing blood to flow more easily and reducing the workload on the heart. It is often combined with other therapies for optimal management of cardiovascular conditions.