Used as a deicing agent on airport runways and pavements, especially where environmental concerns limit the use of chloride-based salts. It is effective at low temperatures and minimizes corrosion to aircraft and infrastructure. Also employed as an antifreeze in cooling systems requiring low temperatures due to its low freezing point and safety advantages over chlorides.

In food processing and pharmaceuticals, it serves as a buffering agent and preservative to control pH and acidity, extend shelf life, and act as an electrolyte replenisher in intravenous fluids for treating potassium deficiency.

In biotechnology and laboratories, it is a component in buffers for separating biomolecules such as proteins or DNA, and in chromatography processes.

Additionally, it functions as a catalyst or reactant in organic synthesis, aids in adjusting dye baths in the textile and leather industries, and is used in some fire extinguishers for kitchen fires involving cooking oils and fats to control reactions effectively and environmentally safely.