Used as a coupling agent in peptide synthesis, facilitating the formation of amide bonds by activating carboxylic acid groups. It is particularly effective in solid-phase peptide synthesis due to its stability and solubility in common organic solvents. Also employed in bioconjugation reactions to link biomolecules such as proteins and antibodies with labels or other functional moieties. Its bifunctional structure allows for cross-linking applications in polymer chemistry and the development of functionalized materials.