Benzyl 1H-benzo[d][1,2,3]triazole-1-carboxylate

95%

Reagent Code: #150968
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CAS Number 57710-80-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 253.26 g/mol
Formula C₁₄H₁₁N₃O₂
badge Registry Numbers
MDL Number MFCD00043157
thermostat Physical Properties
Melting Point 107-109 °C
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Benzyl 1H-benzo[d][1,2,3]triazole-1-carboxylate is a specialized reagent in organic synthesis, primarily used for the protection of amines with the carbobenzyloxy (Cbz or Z) group. In peptide synthesis, it enables the selective N-protection of amino acids and peptides under mild conditions, minimizing side reactions and improving yield compared to traditional chlorides like Cbz-Cl. The benzotriazol-1-yl moiety acts as an efficient leaving group, promoting smooth reaction with nucleophilic amines to form stable carbamate protecting groups that are orthogonal to many other protections. Additionally, it is utilized in the preparation of carbamates, ureas, and other nitrogen-containing heterocycles, with applications in medicinal chemistry and pharmaceutical intermediate synthesis due to its stability, solubility, and compatibility with diverse functional groups.

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Test Parameter Specification
Appearance white solid
Purity (%) 94.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿1,430.00
inventory 5g
10-20 days ฿4,830.00
inventory 25g
10-20 days ฿21,560.00

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