Used as a key Weinreb amide reagent in organic synthesis. It enables the controlled conversion of carboxylic acid derivatives into ketones or aldehydes by reacting with organometallic reagents such as Grignard or organolithium compounds. Its stability and selectivity make it valuable in multi-step synthesis of complex molecules, including natural products and pharmaceuticals. Commonly employed in medicinal chemistry for building carbon–carbon bonds without over-addition side reactions.