Used in pharmaceutical research as a potent and selective antagonist of the orexin OX2 receptor, showing potential for the treatment of insomnia and other sleep disorders. It demonstrates high brain penetration and oral bioavailability in preclinical models, making it a valuable candidate for developing hypnotic agents. Its rigid adamantane and cyclohexylmethyl structure contributes to metabolic stability and target specificity. Also employed as a reference compound in studies evaluating orexin system modulation and sleep-wake regulation.