N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
95%
Reagent
Code: #109002
CAS Number
2245697-85-0
blur_circular Chemical Specifications
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Molecular Information
Weight
587.02 g/mol
Formula
C₂₅H₃₅ClN₄O₁₀
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Registry Numbers
MDL Number
MFCD31656718
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Storage & Handling
Storage
-20°C, store under inert gas
description Product Description
This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.
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N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.
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