N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride

95%

Reagent Code: #109002
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CAS Number 2245697-85-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 587.02 g/mol
Formula C₂₅H₃₅ClN₄O₁₀
badge Registry Numbers
MDL Number MFCD31656718
inventory_2 Storage & Handling
Storage -20°C, store under inert gas

description Product Description

This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿28,611.00
inventory 250mg
10-20 days ฿42,912.00
N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.
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