4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid
10mM in DMSO
Reagent
Code: #142656
CAS Number
16506-27-7
blur_circular Chemical Specifications
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Molecular Information
Weight
358.26 g/mol
Formula
C₁₆H₂₁Cl₂N₃O₂
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Registry Numbers
MDL Number
MFCD00866481
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Storage & Handling
Storage
-20°C
description Product Description
Used as an intermediate in the synthesis of targeted cancer therapies, particularly in the development of antibody-drug conjugates (ADCs). Its structure allows for selective alkylation of DNA, making it valuable in creating cytotoxic agents that can be directed to tumor cells with high specificity. The carboxylic acid group enables conjugation to monoclonal antibodies via linker systems, facilitating controlled drug delivery and reduced systemic toxicity. Commonly employed in research settings for designing novel antitumor compounds with improved pharmacokinetic profiles.
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