Fmoc-Val-Cit-PAB-PNP

98%

Reagent Code: #105918
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CAS Number 863971-53-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 766.8 g/mol
Formula C₄₀H₄₂N₆O₁₀
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in the field of peptide synthesis and drug development, this compound serves as a key intermediate in the creation of antibody-drug conjugates (ADCs). Its structure includes a self-immolative linker, which is crucial for the controlled release of cytotoxic agents in targeted cancer therapies. The Fmoc group protects the amino acid during synthesis, while the PNP ester facilitates coupling reactions. This chemical is particularly valuable in designing prodrugs that enhance the specificity and efficacy of cancer treatments by delivering potent drugs directly to tumor cells, minimizing damage to healthy tissues. Its application is pivotal in advancing precision medicine and improving therapeutic outcomes.

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Test Parameter Specification
Appearance White To Light Yellow To Yellow To Brown Powder Or Crystals
Purity (%) 97.5-100%
Infrared Spectrum Conforms To Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿3,600.00
inventory 250mg
10-20 days ฿9,020.00
inventory 1g
10-20 days ฿32,000.00
Fmoc-Val-Cit-PAB-PNP
Used primarily in the field of peptide synthesis and drug development, this compound serves as a key intermediate in the creation of antibody-drug conjugates (ADCs). Its structure includes a self-immolative linker, which is crucial for the controlled release of cytotoxic agents in targeted cancer therapies. The Fmoc group protects the amino acid during synthesis, while the PNP ester facilitates coupling reactions. This chemical is particularly valuable in designing prodrugs that enhance the specificity and efficacy of cancer treatments by delivering potent drugs directly to tumor cells, minimizing damage to healthy tissues. Its application is pivotal in advancing precision medicine and improving therapeutic outcomes.
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