Fmoc-Val-Cit-PAB-PNP
98%
Reagent
Code: #105918
CAS Number
863971-53-3
blur_circular Chemical Specifications
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Molecular Information
Weight
766.8 g/mol
Formula
C₄₀H₄₂N₆O₁₀
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the field of peptide synthesis and drug development, this compound serves as a key intermediate in the creation of antibody-drug conjugates (ADCs). Its structure includes a self-immolative linker, which is crucial for the controlled release of cytotoxic agents in targeted cancer therapies. The Fmoc group protects the amino acid during synthesis, while the PNP ester facilitates coupling reactions. This chemical is particularly valuable in designing prodrugs that enhance the specificity and efficacy of cancer treatments by delivering potent drugs directly to tumor cells, minimizing damage to healthy tissues. Its application is pivotal in advancing precision medicine and improving therapeutic outcomes.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White To Light Yellow To Yellow To Brown Powder Or Crystals |
Purity (%) | 97.5-100% |
Infrared Spectrum | Conforms To Structure |
NMR | Conforms to Structure |
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Fmoc-Val-Cit-PAB-PNP
Used primarily in the field of peptide synthesis and drug development, this compound serves as a key intermediate in the creation of antibody-drug conjugates (ADCs). Its structure includes a self-immolative linker, which is crucial for the controlled release of cytotoxic agents in targeted cancer therapies. The Fmoc group protects the amino acid during synthesis, while the PNP ester facilitates coupling reactions. This chemical is particularly valuable in designing prodrugs that enhance the specificity and efficacy of cancer treatments by delivering potent drugs directly to tumor cells, minimizing damage to healthy tissues. Its application is pivotal in advancing precision medicine and improving therapeutic outcomes.
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