Triisoamylamine is primarily used as a solvent and extractant in various chemical processes. It is particularly effective in the extraction of metals, such as uranium and plutonium, from aqueous solutions in nuclear fuel reprocessing. Its ability to selectively separate these metals makes it valuable in the nuclear industry. Additionally, it is utilized in organic synthesis as a base or catalyst in certain reactions, aiding in the production of pharmaceuticals and specialty chemicals. Its properties also make it suitable for use in the formulation of corrosion inhibitors and surfactants, contributing to industrial applications where stability and efficiency are crucial.